{"id":8262,"date":"2021-08-14T14:45:45","date_gmt":"2021-08-14T07:45:45","guid":{"rendered":"https:\/\/cdcangiang.vn\/?p=8262"},"modified":"2021-08-14T14:45:45","modified_gmt":"2021-08-14T07:45:45","slug":"doi-tuong-nao-duoc-dung-thuoc-remdesivir-chua-covid-19-theo-huong-dan-cua-bo-y-te","status":"publish","type":"post","link":"https:\/\/cdcangiang.vn\/index.php\/2021\/08\/14\/doi-tuong-nao-duoc-dung-thuoc-remdesivir-chua-covid-19-theo-huong-dan-cua-bo-y-te\/","title":{"rendered":"\u0110\u1ed1i t\u01b0\u1ee3ng n\u00e0o \u0111\u01b0\u1ee3c d\u00f9ng thu\u1ed1c Remdesivir ch\u1eefa COVID-19 theo h\u01b0\u1edbng d\u1eabn c\u1ee7a B\u1ed9 Y t\u1ebf ?"},"content":{"rendered":"<h2 class=\"article-summary\">C\u00e1c b\u1ec7nh vi\u1ec7n ch\u1ec9 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng thu\u1ed1c Remdesivir ch\u1eefa COVID-19 sau khi c\u00f3 s\u1ef1 \u0111\u1ed3ng \u00fd c\u1ee7a b\u1ec7nh nh\u00e2n ho\u1eb7c ng\u01b0\u1eddi nh\u00e0 b\u1ec7nh nh\u00e2n.<\/h2>\n<div class=\"article-body-text\">\n<p>B\u1ed9 Y t\u1ebf v\u1eeba c\u00f3 v\u0103n b\u1ea3n g\u1eedi c\u00e1c \u0111\u01a1n v\u1ecb \u0111\u01b0\u1ee3c ph\u00e2n b\u1ed5, s\u1eed d\u1ee5ng thu\u1ed1c Remdesivir trong \u0111i\u1ec1u tr\u1ecb COVID-19 h\u01b0\u1edbng d\u1eabn tri\u1ec3n khai s\u1eed d\u1ee5ng thu\u1ed1c Remdesivir.<\/p>\n<p>Theo \u0111\u00f3, c\u00e1c b\u1ec7nh vi\u1ec7n ph\u1ea3i th\u00f4ng b\u00e1o v\u1edbi b\u1ec7nh nh\u00e2n ho\u1eb7c ng\u01b0\u1eddi nh\u00e0 b\u1ec7nh nh\u00e2n c\u00e1c th\u00f4ng tin v\u1ec1 vi\u1ec7c thu\u1ed1c \u0111\u01b0\u1ee3c c\u1ea5p ph\u00e9p nh\u1eadp kh\u1ea9u. Ch\u1ec9 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng thu\u1ed1c sau khi c\u00f3 s\u1ef1 \u0111\u1ed3ng \u00fd c\u1ee7a b\u1ec7nh nh\u00e2n ho\u1eb7c ng\u01b0\u1eddi nh\u00e0 b\u1ec7nh nh\u00e2n.<\/p>\n<p>Th\u1ef1c hi\u1ec7n theo d\u00f5i, \u0111\u00e1nh gi\u00e1 hi\u1ec7u qu\u1ea3 \u0111i\u1ec1u tr\u1ecb v\u00e0 an to\u00e0n c\u1ee7a thu\u1ed1c, b\u00e1o c\u00e1o c\u00e1c th\u00f4ng tin g\u1ed3m: S\u1ed1 l\u01b0\u1ee3ng thu\u1ed1c \u0111\u00e3 s\u1eed d\u1ee5ng, hi\u1ec7u qu\u1ea3 \u0111i\u1ec1u tr\u1ecb, \u0111\u1ed9 an to\u00e0n c\u1ee7a thu\u1ed1c Remdesivir g\u1eedi v\u1ec1 B\u1ed9 Y t\u1ebf (C\u1ee5c Qu\u1ea3n l\u00fd Kh\u00e1m, ch\u1eefa b\u1ec7nh, C\u1ee5c Qu\u1ea3n l\u00fd D\u01b0\u1ee3c) v\u00e0o ng\u00e0y 30 h\u00e0ng th\u00e1ng \u0111\u1ec3 t\u1ed5ng h\u1ee3p v\u00e0 \u0111\u1ec1 xu\u1ea5t B\u1ed9 Y t\u1ebf b\u1ed5 sung b\u1ed5 sung h\u01b0\u1edbng d\u1eabn ch\u1ea9n \u0111o\u00e1n v\u00e0 \u0111i\u1ec1u tr\u1ecb COVID-19. B\u1ed9 Y t\u1ebf \u0111\u1ec1 ngh\u1ecb c\u00e1c c\u01a1 s\u1edf kh\u1ea9n tr\u01b0\u01a1ng tri\u1ec3n khai th\u1ef1c hi\u1ec7n v\u00e0 t\u1ed5ng h\u1ee3p b\u00e1o c\u00e1o B\u1ed9 Y t\u1ebf<\/p>\n<p>Theo h\u01b0\u1edbng d\u1eabn t\u1ea1m th\u1eddi s\u1eed d\u1ee5ng thu\u1ed1c Remdesivir 100mg (5mg\/ml) theo h\u01b0\u1edbng d\u1eabn c\u1ee7a C\u1ee5c Qu\u1ea3n l\u00fd Th\u1ef1c ph\u1ea9m v\u00e0 D\u01b0\u1ee3c ph\u1ea9m Hoa K\u1ef3 (FDA Hoa K\u1ef3), C\u01a1 quan qu\u1ea3n l\u00fd D\u01b0\u1ee3c ph\u1ea9m ch\u00e2u \u00c2u (EMA), thu\u1ed1c Remdesivir ch\u1ec9 \u0111\u1ecbnh d\u00f9ng cho ng\u01b0\u1eddi b\u1ec7nh COVID-19 \u0111i\u1ec1u tr\u1ecb n\u1ed9i tr\u00fa t\u1ea1i b\u1ec7nh vi\u1ec7n c\u00f3 suy h\u00f4 h\u1ea5p ph\u1ea3i th\u1edf oxy, th\u1edf HFNC, ho\u1eb7c th\u1edf m\u00e1y kh\u00f4ng x\u00e2m nh\u1eadp.<\/p>\n<figure id=\"attachment_8263\" aria-describedby=\"caption-attachment-8263\" style=\"width: 596px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-8263\" src=\"https:\/\/cdcangiang.vn\/wp-content\/uploads\/2021\/08\/1111-16.jpg\" alt=\"\" width=\"596\" height=\"335\" srcset=\"https:\/\/cdcangiang.vn\/wp-content\/uploads\/2021\/08\/1111-16.jpg 596w, https:\/\/cdcangiang.vn\/wp-content\/uploads\/2021\/08\/1111-16-300x169.jpg 300w\" sizes=\"auto, (max-width: 596px) 100vw, 596px\" \/><figcaption id=\"caption-attachment-8263\" class=\"wp-caption-text\">Ch\u1ec9 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng thu\u1ed1c Remdesivir sau khi c\u00f3 s\u1ef1 \u0111\u1ed3ng \u00fd c\u1ee7a b\u1ec7nh nh\u00e2n ho\u1eb7c ng\u01b0\u1eddi nh\u00e0 b\u1ec7nh nh\u00e2n<\/figcaption><\/figure>\n<p><strong>Th\u1eddi \u0111i\u1ec3m d\u00f9ng thu\u1ed1c Remdesivir<\/strong><\/p>\n<p>Trong v\u00f2ng 10 ng\u00e0y \u0111\u1ea7u t\u1eeb khi kh\u1edfi ph\u00e1t b\u1ec7nh v\u00e0 n\u00ean ph\u1ed1i h\u1ee3p v\u1edbi Dexamethasone.<\/p>\n<p>Theo h\u01b0\u1edbng d\u1eabn c\u1ee7a B\u1ed9 Y t\u1ebf, thu\u1ed1c n\u00e0y \u01b0u ti\u00ean s\u1eed d\u1ee5ng cho nh\u00f3m nguy c\u01a1 cao g\u1ed3mng\u01b0\u1eddi tr\u00ean 65 tu\u1ed5i, ng\u01b0\u1eddi c\u00f3 b\u1ec7nh n\u1ec1n, b\u00e9o ph\u00ec (BMI &gt;25).<\/p>\n<p>B\u1ed9 Y t\u1ebf l\u01b0u \u00fd kh\u00f4ng b\u1eaft \u0111\u1ea7u s\u1eed d\u1ee5ng thu\u1ed1c cho ng\u01b0\u1eddi b\u1ec7nh COVID-19 c\u1ea7n th\u1edf m\u00e1y x\u00e2m nh\u1eadp, ECMO.<\/p>\n<p>Ri\u00eang \u0111\u1ed1i v\u1edbi c\u00e1c tr\u01b0\u1eddng h\u1ee3p \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Remdesivir tr\u01b0\u1edbc khi th\u1edf m\u00e1y x\u00e2m nh\u1eadp ho\u1eb7c ECMO th\u00ec ti\u1ebfp t\u1ee5c d\u00f9ng Remdesivir cho \u0111\u1ee7 li\u1ec7u tr\u00ecnh.<\/p>\n<p>H\u01b0\u1edbng d\u1eabn c\u1ee7a B\u1ed9 Y t\u1ebf c\u0169ng n\u00eau r\u00f5 thu\u1ed1c n\u00e0y ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh v\u1edbi tr\u01b0\u1eddng h\u1ee3p ph\u1ea3n \u1ee9ng qu\u00e1 m\u1eabn v\u1edbi b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n c\u1ee7a thu\u1ed1c; Suy ch\u1ee9c n\u0103ng th\u1eadn eGFR 5 l\u1ea7n gi\u00e1 tr\u1ecb gi\u1edbi h\u1ea1n tr\u00ean; Suy ch\u1ee9c n\u0103ng \u0111a c\u01a1 quan n\u1eb7ng<\/p>\n<p><strong>Th\u1eadn tr\u1ecdng s\u1eed d\u1ee5ng thu\u1ed1c Remdesivir v\u1edbi ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa<\/strong><\/p>\n<p>V\u1ec1 li\u1ec1u v\u00e0 c\u00e1ch s\u1eed d\u1ee5ng<\/p>\n<p>Ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb em \u2265 12 tu\u1ed5i, c\u00e2n n\u1eb7ng &gt; 40kg<\/p>\n<p>+ Ng\u00e0y \u0111\u1ea7u ti\u00ean: li\u1ec1u 200mg truy\u1ec1n t\u0129nh m\u1ea1ch trong v\u00f2ng 30 \u2013 120 ph\u00fat, nh\u1eefng ng\u00e0y sau li\u1ec1u: 100mg truy\u1ec1n t\u0129nh m\u1ea1ch, trong 2-5 ng\u00e0y. \u0110\u1ed1i v\u1edbi b\u1ec7nh nh\u00e2n kh\u00f4ng th\u1ea5y c\u1ea3i thi\u1ec7n v\u1ec1 m\u1eb7t l\u00e2m s\u00e0ng sau 5 ng\u00e0y \u0111i\u1ec1u tr\u1ecb th\u00ec c\u00f3 th\u1ec3 \u0111i\u1ec1u tr\u1ecb ti\u1ebfp li\u1ec1u n\u00e0y (100mg) cho \u0111\u1ebfn 10 ng\u00e0y.<\/p>\n<p>+ C\u00e1ch d\u00f9ng: l\u1ea5y 19 ml n\u01b0\u1edbc c\u1ea5t pha v\u00e0o l\u1ecd thu\u1ed1c Remdesivir 100mg \u0111\u1ec3 \u0111\u01b0\u1ee3c 20 ml thu\u1ed1c sau \u0111\u00f3 pha v\u1edbi 230ml Nacl 0,9% truy\u1ec1n t\u0129nh m\u1ea1ch trong v\u00f2ng 30 \u2013 120 ph\u00fat.<\/p>\n<p>Tr\u1ebb em &lt; 12 tu\u1ed5i, c\u00e2n n\u1eb7ng t\u1eeb 3,5 \u0111\u1ebfn 40kg<\/p>\n<p>+ Ng\u00e0y \u0111\u1ea7u ti\u00ean: li\u1ec1u 5mg\/kg\/li\u1ec1u, nh\u1eefng ng\u00e0y sau li\u1ec1u: 2,5mg\/kg\/li\u1ec1u truy\u1ec1n t\u0129nh m\u1ea1ch, trong 2-5 ng\u00e0y.<\/p>\n<p>\u0110\u1ed1i v\u1edbi b\u1ec7nh nh\u00e2n kh\u00f4ng th\u1ea5y c\u1ea3i thi\u1ec7n v\u1ec1 m\u1eb7t l\u00e2m s\u00e0ng sau 5 ng\u00e0y \u0111i\u1ec1u tr\u1ecb th\u00ec c\u00f3 th\u1ec3 \u0111i\u1ec1u tr\u1ecb ti\u1ebfp li\u1ec1u n\u00e0y (2,5mg\/kg\/li\u1ec1u) cho \u0111\u1ebfn 10 ng\u00e0y .<\/p>\n<p>+ C\u00e1ch d\u00f9ng: l\u1ea5y 19ml n\u01b0\u1edbc c\u1ea5t pha v\u00e0o l\u1ecd thu\u1ed1c Remdesivir 100mg \u0111\u1ec3 \u0111\u01b0\u1ee3c 20ml thu\u1ed1c, l\u1ea5y s\u1ed1 l\u01b0\u1ee3ng thu\u1ed1c \u0111\u00e3 pha t\u00ednh theo c\u00e2n n\u1eb7ng pha v\u1edbi Nacl 0,9% \u0111\u1ec3 \u0111\u01b0\u1ee3c n\u1ed3ng \u0111\u1ed9 remdesivir 1,25 mg\/mL, truy\u1ec1n t\u0129nh m\u1ea1ch trong 30-120 ph\u00fat.<\/p>\n<p>Tr\u1ebb em d\u01b0\u1edbi 12 tu\u1ed5i v\u00e0 c\u00e2n n\u1eb7ng \u2265 40 kg: \u00e1p d\u1ee5ng gi\u1ed1ng li\u1ec1u c\u1ee7a ng\u01b0\u1eddi l\u1edbn<\/p>\n<p>B\u1ed9 Y t\u1ebf l\u01b0u \u00fd thu\u1ed1c n\u00e0y th\u1eadn tr\u1ecdng s\u1eed d\u1ee5ng v\u1edbi ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa: Ch\u01b0a c\u00f3 d\u1eef li\u1ec7u \u0111\u1ea7y \u0111\u1ee7. Kh\u00f4ng khuy\u1ebfn c\u00e1o tr\u1eeb tr\u01b0\u1eddng h\u1ee3p l\u1ee3i \u00edch v\u01b0\u1ee3t tr\u1ed9i so v\u1edbi nguy c\u01a1.<\/p>\n<p>Ng\u01b0\u1eddi suy gi\u1ea3m ch\u1ee9c n\u0103ng th\u1eadn: Ch\u01b0a c\u00f3 d\u1eef li\u1ec7u \u0111\u00e1nh gi\u00e1, nh\u01b0ng v\u1edbi eGFR \u00b3 30 mL\/ph\u00fat, kh\u00f4ng c\u1ea7n ch\u1ec9nh li\u1ec1u.<\/p>\n<p>X\u00e9t nghi\u1ec7m enzyme gan ALT v\u00e0 th\u1eddi gian prothrombin (PT) tr\u01b0\u1edbc khi ch\u1ec9 \u0111\u1ecbnh.<\/p>\n<p>\u0110\u1eb7c bi\u1ec7t kh\u00f4ng truy\u1ec1n Remdesivir c\u00f9ng l\u00fac v\u1edbi c\u00e1c thu\u1ed1c kh\u00e1c.<\/p>\n<p>H\u01b0\u1edbng d\u1eabn c\u1ee7a B\u1ed9 Y t\u1ebf cho bi\u1ebft thu\u1ed1c n\u00e0y c\u00f3 c\u00e1c t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n nh\u01b0 ; C\u00e1c ph\u1ea3n \u1ee9ng do qu\u00e1 m\u1eabn nh\u01b0 r\u1ee5t huy\u1ebft \u00e1p, bu\u1ed3n n\u00f4n, n\u00f4n, ch\u1ea3y m\u1ed3 h\u00f4i, r\u00f9ng m\u00ecnh.<\/p>\n<p>N\u00ean l\u1ef1a ch\u1ecdn truy\u1ec1n ch\u1eadm trong 120 ph\u00fat \u0111\u1ec3 h\u1ea1n ch\u1ebf t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n\u2026<\/p>\n<p style=\"text-align: right;\"><em><strong>Ngu\u1ed3n B\u1ed9 Y t\u1ebf<\/strong><\/em><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>C\u00e1c b\u1ec7nh vi\u1ec7n ch\u1ec9 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng thu\u1ed1c Remdesivir ch\u1eefa COVID-19 sau khi c\u00f3 s\u1ef1 \u0111\u1ed3ng \u00fd c\u1ee7a b\u1ec7nh nh\u00e2n ho\u1eb7c ng\u01b0\u1eddi nh\u00e0 b\u1ec7nh nh\u00e2n. B\u1ed9 Y t\u1ebf v\u1eeba c\u00f3 v\u0103n b\u1ea3n g\u1eedi c\u00e1c \u0111\u01a1n v\u1ecb \u0111\u01b0\u1ee3c ph\u00e2n b\u1ed5, s\u1eed d\u1ee5ng thu\u1ed1c Remdesivir trong \u0111i\u1ec1u tr\u1ecb COVID-19 h\u01b0\u1edbng d\u1eabn tri\u1ec3n khai s\u1eed d\u1ee5ng thu\u1ed1c Remdesivir. [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":8263,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"limit_modified_date":"","last_modified_date":"","footnotes":""},"categories":[241],"tags":[],"class_list":["post-8262","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cap-nhat-tin-covid"],"_links":{"self":[{"href":"https:\/\/cdcangiang.vn\/index.php\/wp-json\/wp\/v2\/posts\/8262","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cdcangiang.vn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cdcangiang.vn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cdcangiang.vn\/index.php\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/cdcangiang.vn\/index.php\/wp-json\/wp\/v2\/comments?post=8262"}],"version-history":[{"count":0,"href":"https:\/\/cdcangiang.vn\/index.php\/wp-json\/wp\/v2\/posts\/8262\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cdcangiang.vn\/index.php\/wp-json\/wp\/v2\/media\/8263"}],"wp:attachment":[{"href":"https:\/\/cdcangiang.vn\/index.php\/wp-json\/wp\/v2\/media?parent=8262"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cdcangiang.vn\/index.php\/wp-json\/wp\/v2\/categories?post=8262"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cdcangiang.vn\/index.php\/wp-json\/wp\/v2\/tags?post=8262"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}