{"id":16589,"date":"2022-11-29T08:18:51","date_gmt":"2022-11-29T01:18:51","guid":{"rendered":"https:\/\/cdcangiang.vn\/?p=16589"},"modified":"2022-11-29T08:18:51","modified_gmt":"2022-11-29T01:18:51","slug":"nhom-nghien-cuu-tu-dh-osaka-metropolitan-tao-ra-mot-loai-vaccine-giup-kich-hoat-cac-te-bao-mien-dich-chong-ung-thu","status":"publish","type":"post","link":"https:\/\/cdcangiang.vn\/index.php\/2022\/11\/29\/nhom-nghien-cuu-tu-dh-osaka-metropolitan-tao-ra-mot-loai-vaccine-giup-kich-hoat-cac-te-bao-mien-dich-chong-ung-thu\/","title":{"rendered":"Nh\u00f3m nghi\u00ean c\u1ee9u t\u1eeb \u0110H Osaka Metropolitan t\u1ea1o ra m\u1ed9t lo\u1ea1i vaccine gi\u00fap k\u00edch ho\u1ea1t c\u00e1c t\u1ebf b\u00e0o mi\u1ec5n d\u1ecbch ch\u1ed1ng ung th\u01b0"},"content":{"rendered":"

C\u00f4ng tr\u00ecnh \u0111\u01b0\u1ee3c c\u00f4ng b\u1ed1 tr\u00ean t\u1ea1p ch\u00ed khoa h\u1ecdc Journal of Controlled Release, ng\u00e0y 3\/11. C\u00e1c chuy\u00ean gia \u0111\u00e3 t\u1ea1o ra ch\u1ea5t mang kh\u00e1ng nguy\u00ean – s\u1eed d\u1ee5ng liposome d\u1ef1a tr\u00ean c\u00e1c ph\u00e2n t\u1eed lipid c\u00f3 k\u00edch th\u01b0\u1edbc nano – \u0111\u1ec3 v\u1eadn chuy\u1ec3n c\u00e1c kh\u00e1ng nguy\u00ean ung th\u01b0 \u0111\u1ebfn t\u1ebf b\u00e0o \u0111u\u00f4i gai. T\u1ebf b\u00e0o n\u00e0y c\u00f3 ch\u1ee9c n\u0103ng nh\u01b0 trung t\u00e2m \u0111i\u1ec1u khi\u1ec3n h\u1ec7 th\u1ed1ng mi\u1ec5n d\u1ecbch.<\/p>\n

Nh\u00f3m \u0111\u00e3 t\u1ea1o ra lo\u1ea1i liposome c\u00f3 t\u00e1c d\u1ee5ng k\u00edch ho\u1ea1t t\u1ebf b\u00e0o mi\u1ec5n d\u1ecbch, ch\u1ec9 c\u1ea7n s\u1eed d\u1ee5ng 10% l\u01b0\u1ee3ng kh\u00e1ng nguy\u00ean c\u1ea7n thi\u1ebft tr\u01b0\u1edbc \u0111\u00f3. \u0110\u1ec3 t\u0103ng c\u01b0\u1eddng hi\u1ec7u qu\u1ea3 c\u1ee7a c\u00e1c liposome n\u00e0y, t\u1ebf b\u00e0o mi\u1ec5n d\u1ecbch c\u1ea7n \u0111\u01b0\u1ee3c k\u00edch ho\u1ea1t m\u1ed9t c\u00e1ch hi\u1ec7u qu\u1ea3 h\u01a1n. Do \u0111\u00f3, nh\u00f3m chuy\u00ean gia t\u1eadp trung v\u00e0o c\u00e1c ch\u1ea5t b\u00e9o cation, \u0111\u01b0\u1ee3c cho l\u00e0 c\u00f3 t\u00e1c d\u1ee5ng th\u00fac \u0111\u1ea9y t\u1ebf b\u00e0o mi\u1ec5n d\u1ecbch ho\u1ea1t \u0111\u1ed9ng.<\/p>\n

Khi s\u1eed d\u1ee5ng vaccine liposome ti\u00eam cho chu\u1ed9t \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1ea5y t\u1ebf b\u00e0o ung th\u01b0, c\u00e1c nh\u00e0 khoa h\u1ecdc nh\u1eadn th\u1ea5y ch\u00fang ph\u00e1t tri\u1ec3n ph\u1ea3n \u1ee9ng mi\u1ec5n d\u1ecbch m\u1ea1nh m\u1ebd, l\u00e0m gi\u1ea3m s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a ung th\u01b0.<\/p>\n

“Trong t\u01b0\u01a1ng lai, ch\u00fang t\u00f4i s\u1ebd ti\u1ebfp t\u1ee5c \u0111i\u1ec1u ch\u1ebf c\u00e1c ch\u1ea5t mang kh\u00e1ng nguy\u00ean c\u00f3 th\u1ec3 s\u1eed d\u1ee5ng trong li\u1ec7u ph\u00e1p mi\u1ec5n d\u1ecbch ung th\u01b0, t\u1ea1o ra c\u00e1c vaccine cho c\u00e1c b\u1ec7nh truy\u1ec1n nhi\u1ec5m b\u1eb1ng c\u00e1ch k\u1ebft h\u1ee3p ch\u00fang v\u1edbi c\u00e1c kh\u00e1ng nguy\u00ean th\u1ef1c t\u1ebf”, ph\u00f3 gi\u00e1o s\u01b0 Eiji Yuba, \u0110\u1ea1i h\u1ecdc Osaka Metropolitan, t\u00e1c gi\u1ea3 ch\u00ednh c\u1ee7a nghi\u00ean c\u1ee9u, cho bi\u1ebft.<\/p>\n

N\u1ebfu c\u00f4ng ngh\u1ec7 n\u00e0y \u0111\u01b0\u1ee3c \u00e1p d\u1ee5ng v\u00e0o th\u1ef1c t\u1ebf, n\u00f3 c\u00f3 th\u1ec3 m\u1edf r\u1ed9ng c\u00e1c \u0111\u1ed1i t\u01b0\u1ee3ng m\u1eafc b\u1ec7nh ung th\u01b0 \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng li\u1ec7u ph\u00e1p mi\u1ec5n d\u1ecbch.<\/p>\n

\"\"
T\u1ebf b\u00e0o ung th\u01b0 \u0111ang ph\u00e2n chia. \u1ea2nh: iStock<\/figcaption><\/figure>\n

Vi\u1ec7c s\u1eed d\u1ee5ng li\u1ec7u ph\u00e1p mi\u1ec5n d\u1ecbch \u0111i\u1ec1u tr\u1ecb ung th\u01b0 \u0111\u01b0\u1ee3c ch\u00fa \u00fd trong th\u1eddi gian g\u1ea7n \u0111\u00e2y. Th\u00e1ng 8, c\u00e1c nh\u00e0 khoa h\u1ecdc \u0111\u00e3 th\u1eed nghi\u1ec7m th\u00e0nh c\u00f4ng thu\u1ed1c \u0111i\u1ec1u tr\u1ecb mi\u1ec5n d\u1ecbch c\u00f3 t\u00ean dostarlimab. Thu\u1ed1c gi\u00fap ch\u1eefa kh\u1ecfi\u00a0ung th\u01b0 tr\u1ef1c tr\u00e0ng<\/a>\u00a0cho 12 t\u00ecnh nguy\u1ec7n vi\u00ean c\u1ee7a th\u1eed nghi\u1ec7m k\u00e9o d\u00e0i 6 th\u00e1ng.<\/p>\n

Dostarlimab kh\u00f4ng ho\u1ea1t \u0111\u1ed9ng b\u1eb1ng c\u00e1ch t\u1ea5n c\u00f4ng tr\u1ef1c ti\u1ebfp v\u00e0o ch\u00ednh kh\u1ed1i u ung th\u01b0, m\u00e0 th\u00fac \u0111\u1ea9y h\u1ec7 th\u1ed1ng mi\u1ec5n d\u1ecbch c\u1ee7a b\u1ec7nh nh\u00e2n th\u1ef1c hi\u1ec7n \u0111i\u1ec1u n\u00e0y.<\/p>\n

Th\u00f4ng th\u01b0\u1eddng, t\u1ebf b\u00e0o T (t\u1ebf b\u00e0o mi\u1ec5n d\u1ecbch) c\u00f3 nhi\u1ec7m v\u1ee5 t\u00ecm ki\u1ebfm v\u00e0 ki\u1ec3m so\u00e1t c\u00e1c m\u1ea7m b\u1ec7nh l\u1ea1. Ch\u00fang ch\u1ee9a hai lo\u1ea1i protein: lo\u1ea1i m\u1ed9t gi\u00fap k\u00edch ho\u1ea1t ph\u1ea3n \u1ee9ng mi\u1ec5n d\u1ecbch, lo\u1ea1i hai h\u1ea1n ch\u1ebf kh\u1ea3 n\u0103ng mi\u1ec5n d\u1ecbch. \u0110\u00e2y \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 nh\u1eefng protein \u0111i\u1ec3m ki\u1ec3m so\u00e1t.<\/p>\n

M\u1ed9t s\u1ed1 t\u1ebf b\u00e0o ung th\u01b0 t\u1ea1o ra l\u01b0\u1ee3ng protein lo\u1ea1i hai cao. Ch\u00fang b\u1ea5t ho\u1ea1t t\u1ebf b\u00e0o T tr\u01b0\u1edbc khi kh\u1ed1i u bi\u1ebfn m\u1ea5t. N\u00f3i c\u00e1ch kh\u00e1c, t\u1ebf b\u00e0o ung th\u01b0 khi\u1ebfn h\u1ec7 mi\u1ec5n d\u1ecbch \u1edf ng\u01b0\u1eddi b\u1ec7nh \u0111\u00ecnh tr\u1ec7.<\/p>\n

Thu\u1ed1c dostarlimab ng\u0103n ch\u1eb7n c\u00e1c protein \u0111i\u1ec3m ki\u1ec3m so\u00e1t lo\u1ea1i hai, t\u1ee9c l\u00e0 ng\u0103n ch\u1eb7n \u1ea3nh h\u01b0\u1edfng c\u1ee7a t\u1ebf b\u00e0o ung th\u01b0 l\u00ean h\u1ec7 mi\u1ec5n d\u1ecbch. Khi h\u1ec7 mi\u1ec5n d\u1ecbch ho\u1ea1t \u0111\u1ed9ng tr\u1edf l\u1ea1i, c\u00e1c t\u1ebf b\u00e0o T c\u00f3 th\u1ec3 t\u00ecm th\u1ea5y v\u00e0 t\u1ea5n c\u00f4ng t\u1ebf b\u00e0o ung th\u01b0.\/.<\/p>\n

Ngu\u1ed3n Vi\u1ec7n Pastuer TP. HCM<\/em><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

C\u00f4ng tr\u00ecnh \u0111\u01b0\u1ee3c c\u00f4ng b\u1ed1 tr\u00ean t\u1ea1p ch\u00ed khoa h\u1ecdc Journal of Controlled Release, ng\u00e0y 3\/11. C\u00e1c chuy\u00ean gia \u0111\u00e3 t\u1ea1o ra ch\u1ea5t mang kh\u00e1ng nguy\u00ean – s\u1eed d\u1ee5ng liposome d\u1ef1a tr\u00ean c\u00e1c ph\u00e2n t\u1eed lipid c\u00f3 k\u00edch th\u01b0\u1edbc nano – \u0111\u1ec3 v\u1eadn chuy\u1ec3n c\u00e1c kh\u00e1ng nguy\u00ean ung th\u01b0 \u0111\u1ebfn t\u1ebf b\u00e0o \u0111u\u00f4i gai. T\u1ebf […]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"limit_modified_date":"","last_modified_date":"","footnotes":""},"categories":[4],"tags":[],"class_list":["post-16589","post","type-post","status-publish","format-standard","hentry","category-ban-tin-tong-hop"],"_links":{"self":[{"href":"https:\/\/cdcangiang.vn\/index.php\/wp-json\/wp\/v2\/posts\/16589","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cdcangiang.vn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cdcangiang.vn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cdcangiang.vn\/index.php\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/cdcangiang.vn\/index.php\/wp-json\/wp\/v2\/comments?post=16589"}],"version-history":[{"count":1,"href":"https:\/\/cdcangiang.vn\/index.php\/wp-json\/wp\/v2\/posts\/16589\/revisions"}],"predecessor-version":[{"id":16591,"href":"https:\/\/cdcangiang.vn\/index.php\/wp-json\/wp\/v2\/posts\/16589\/revisions\/16591"}],"wp:attachment":[{"href":"https:\/\/cdcangiang.vn\/index.php\/wp-json\/wp\/v2\/media?parent=16589"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cdcangiang.vn\/index.php\/wp-json\/wp\/v2\/categories?post=16589"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cdcangiang.vn\/index.php\/wp-json\/wp\/v2\/tags?post=16589"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}