Molnupiravir l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c ho\u1ea1t \u0111\u1ed9ng b\u1eb1ng c\u00e1ch \u0111\u01b0a c\u00e1c \u0111\u1ed9t bi\u1ebfn v\u00e0o m\u00e3 di truy\u1ec1n c\u1ee7a vi r\u00fat SARS-CoV-2, ng\u0103n ch\u1eb7n s\u1ef1 t\u00e1i t\u1ea1o c\u1ee7a vi r\u00fat. Qua \u0111\u00f3 c\u00f3 hi\u1ec7u qu\u1ea3 trong vi\u1ec7c \u0111i\u1ec1u tr\u1ecb b\u1ec7nh COVID-19. Hi\u1ec7u qu\u1ea3 n\u00e0y \u0111\u01b0\u1ee3c th\u1ec3 hi\u1ec7n trong m\u1ed9t th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng ng\u1eabu nhi\u00ean, m\u00f9 \u0111\u00f4i, c\u00f3 \u0111\u1ed1i ch\u1ee9ng v\u1edbi gi\u1ea3 d\u01b0\u1ee3c cho th\u1ea5y trong s\u1ed1 709 ng\u01b0\u1eddi \u0111\u01b0\u1ee3c d\u00f9ng Molnupiravir ch\u1ec9 c\u00f3 6,8% b\u1ec7nh nh\u00e2n ph\u1ea3i nh\u1eadp vi\u1ec7n ho\u1eb7c t\u1eed vong v\u00ec COVID-19 so v\u1edbi 9,7% trong s\u1ed1 699 ng\u01b0\u1eddi \u0111\u01b0\u1ee3c d\u00f9ng gi\u1ea3 d\u01b0\u1ee3c. C\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 \u0111\u01b0\u1ee3c quan s\u00e1t th\u1ea5y trong th\u1eed nghi\u1ec7m bao g\u1ed3m ti\u00eau ch\u1ea3y, bu\u1ed3n n\u00f4n v\u00e0 ch\u00f3ng m\u1eb7t. T\u00ednh an to\u00e0n v\u00e0 hi\u1ec7u qu\u1ea3 c\u1ee7a Molnupiravir \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb COVID-19 \u0111ang ti\u1ebfp t\u1ee5c \u0111\u01b0\u1ee3c \u0111\u00e1nh gi\u00e1.<\/p>\n
Ng\u00e0y 23\/12\/2021, Molnupiravir \u0111\u00e3 \u0111\u01b0\u1ee3c C\u1ee5c qu\u1ea3n l\u00fd Th\u1ef1c ph\u1ea9m v\u00e0 D\u01b0\u1ee3c ph\u1ea9m Hoa K\u1ef3 (FDA) c\u1ea5p ph\u00e9p s\u1eed d\u1ee5ng kh\u1ea9n c\u1ea5p \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh COVID-19 t\u1eeb nh\u1eb9 \u0111\u1ebfn trung b\u00ecnh \u1edf ng\u01b0\u1eddi l\u1edbn. Li\u1ec1u d\u00f9ng l\u00e0 u\u1ed1ng 800mg Molnupiravir m\u00f4\u0303i 12 gi\u01a1\u0300 trong 5 nga\u0300y. FDA c\u0169ng khuy\u1ebfn c\u00e1o m\u1ed9t s\u1ed1 l\u01b0u \u00fd v\u1ec1 Molnupiravir bao g\u1ed3m:<\/p>\n
– Kh\u00f4ng \u0111\u01b0\u1ee3c ph\u00e9p s\u1eed d\u1ee5ng cho b\u1ec7nh nh\u00e2n d\u01b0\u1edbi 18 tu\u1ed5i v\u00ec Molnupiravir c\u00f3 th\u1ec3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a x\u01b0\u01a1ng v\u00e0 s\u1ee5n.<\/p>\n
– Kh\u00f4ng \u0111\u01b0\u1ee3c ph\u00e9p cho vi\u1ec7c ph\u00f2ng ng\u1eeba tr\u01b0\u1edbc ho\u1eb7c sau ph\u01a1i nhi\u1ec5m v\u1edbi COVID-19 ho\u1eb7c b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb \u1edf b\u1ec7nh nh\u00e2n nh\u1eadp vi\u1ec7n do COVID-19.<\/p>\n
– Kh\u00f4ng th\u1ec3 thay th\u1ebf cho vi\u1ec7c ti\u00eam ch\u1ee7ng v\u1eafc xin ph\u00f2ng COVID-19.<\/p>\n
– Kh\u00f4ng \u0111\u01b0\u1ee3c khuy\u1ebfn c\u00e1o s\u1eed d\u1ee5ng trong th\u1eddi k\u1ef3 mang thai, v\u00ec c\u00f3 th\u1ec3 g\u00e2y h\u1ea1i cho thai nhi. Molnupiravir ch\u1ec9 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef mang thai khi b\u00e1c s\u0129 \u0111\u00e3 x\u00e1c \u0111\u1ecbnh r\u1eb1ng l\u1ee3i \u00edch c\u1ee7a vi\u1ec7c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Molnupiravir s\u1ebd l\u1edbn h\u01a1n nguy c\u01a1. Nh\u1eefng ph\u1ee5 n\u1eef c\u00f3 d\u1ef1 \u0111\u1ecbnh mang thai n\u00ean s\u1eed d\u1ee5ng m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p ng\u1eeba thai trong b\u1ed1n ng\u00e0y sau li\u1ec1u Molnupiravir cu\u1ed1i c\u00f9ng.<\/p>\n
Ngo\u00e0i ra, theo khuy\u1ebfn c\u00e1o c\u1ee7a Vi\u1ec7n Y t\u1ebf qu\u1ed1c gia Hoa K\u1ef3 (NIH) ch\u1ec9 n\u00ean s\u1eed d\u1ee5ng Molnupiravir khi c\u00e1c thu\u1ed1c Nirmatrelvir, Sotrovimab v\u00e0 Remdesivir t\u0103ng c\u01b0\u1eddng Ritonavir kh\u00f4ng c\u00f3 s\u1eb5n ho\u1eb7c kh\u00f4ng th\u1ec3 s\u1eed d\u1ee5ng \u0111\u01b0\u1ee3c, v\u00ec Molnupiravir c\u00f3 hi\u1ec7u qu\u1ea3 th\u1ea5p h\u01a1n c\u00e1c l\u1ef1a ch\u1ecdn tr\u00ean.<\/p>\n
Trong b\u1ed1i c\u1ea3nh hi\u1ec7n nay, B\u1ed9 Y t\u1ebf \u0111\u00e3 c\u1ea5p ph\u00e9p 3 thu\u1ed1c ch\u1ee9a ho\u1ea1t ch\u1ea5t Molnupiravir \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t v\u00e0 l\u01b0u h\u00e0nh trong n\u01b0\u1edbc nh\u1eb1m gi\u00fap ng\u01b0\u1eddi m\u1eafc COVID-19 m\u1ee9c \u0111\u1ed9 nh\u1eb9 v\u00e0 trung b\u00ecnh c\u00f3 th\u00eam c\u01a1 h\u1ed9i l\u1ef1a ch\u1ecdn thu\u1ed1c \u0111i\u1ec1u tr\u1ecb. Tuy nhi\u00ean, kh\u00f4ng ph\u1ea3i b\u1ec7nh nh\u00e2n n\u00e0o c\u0169ng c\u00f3 th\u1ec3 s\u1eed d\u1ee5ng thu\u1ed1c. Do \u0111\u00f3, c\u1ea7n th\u1eadn tr\u1ecdng khi s\u1eed d\u1ee5ng thu\u1ed1c Molnupiravir theo \u0111\u00fang ch\u1ec9 \u0111\u1ecbnh c\u1ee7a b\u00e1c s\u0129 v\u00e0 \u0111\u1ecdc k\u1ef9 h\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng t\u1eeb nh\u00e0 s\u1ea3n xu\u1ea5t \u0111\u1ec3 \u0111\u1ea3m b\u1ea3o t\u00ednh an to\u00e0n v\u00e0 hi\u1ec7u qu\u1ea3.<\/p>\n
Th\u1ee7y Ti\u00ean<\/em><\/p>\n Trung t\u00e2m Ki\u1ec3m so\u00e1t b\u1ec7nh t\u1eadt TP.HCM (t\u1ed5ng h\u1ee3p)<\/em><\/p>\n","protected":false},"excerpt":{"rendered":" Molnupiravir l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c ho\u1ea1t \u0111\u1ed9ng b\u1eb1ng c\u00e1ch \u0111\u01b0a c\u00e1c \u0111\u1ed9t bi\u1ebfn v\u00e0o m\u00e3 di truy\u1ec1n c\u1ee7a vi r\u00fat SARS-CoV-2, ng\u0103n ch\u1eb7n s\u1ef1 t\u00e1i t\u1ea1o c\u1ee7a vi r\u00fat. Qua \u0111\u00f3 c\u00f3 hi\u1ec7u qu\u1ea3 trong vi\u1ec7c \u0111i\u1ec1u tr\u1ecb b\u1ec7nh COVID-19. Hi\u1ec7u qu\u1ea3 n\u00e0y \u0111\u01b0\u1ee3c th\u1ec3 hi\u1ec7n trong m\u1ed9t th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng ng\u1eabu nhi\u00ean, m\u00f9 […]<\/p>\n","protected":false},"author":4,"featured_media":11350,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"limit_modified_date":"","last_modified_date":"","footnotes":""},"categories":[241,235,239],"tags":[],"class_list":["post-13088","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cap-nhat-tin-covid","category-phong-chong-covid-19","category-truyen-thong-theo-chu-de"],"_links":{"self":[{"href":"https:\/\/cdcangiang.vn\/index.php\/wp-json\/wp\/v2\/posts\/13088","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cdcangiang.vn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cdcangiang.vn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cdcangiang.vn\/index.php\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/cdcangiang.vn\/index.php\/wp-json\/wp\/v2\/comments?post=13088"}],"version-history":[{"count":1,"href":"https:\/\/cdcangiang.vn\/index.php\/wp-json\/wp\/v2\/posts\/13088\/revisions"}],"predecessor-version":[{"id":13089,"href":"https:\/\/cdcangiang.vn\/index.php\/wp-json\/wp\/v2\/posts\/13088\/revisions\/13089"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cdcangiang.vn\/index.php\/wp-json\/wp\/v2\/media\/11350"}],"wp:attachment":[{"href":"https:\/\/cdcangiang.vn\/index.php\/wp-json\/wp\/v2\/media?parent=13088"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cdcangiang.vn\/index.php\/wp-json\/wp\/v2\/categories?post=13088"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cdcangiang.vn\/index.php\/wp-json\/wp\/v2\/tags?post=13088"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}